One of the easiest ways to give is not to write a check or even donate your time, though these are valuable means of contributing to charitable organizations, is to send off a used t-shirt to someone who does not have one. A group called One Million T-Shirts is collecting your used shirts and giving them to children and adults in Africa who might otherwise go shirtless.
The group is also asking that you include a dollar, but this seems like a tiny donation given the fact that they're doing all of the shipping and distributing of the shirts. More than a way to save a life, this might just be a simple good deed that will show others that the world cares. I have seen a couple of negative reviews of this project, but I think it's brilliant in its simplicity. I don't think that organizers of this project think that giving away t-shirts will end poverty in Africa, but hope that organizing groups of people to do something and spreading awareness will encourage more charitable acts.
Send your shirt and spread the word on the group's facebook page!